Peer-reviewed publications surrounding NanoJacket Technology

• Nanoparticulate alternatives for drug delivery. Adair et al, 2010. ACS Nano. 4(9):4967-4970
• Near infrared imaging with nanoparticles. Altinoglu et al, 2010. Wiley Interdisciplinary Reviews - Nanomedicine and Nanobiotechnology 2(5):461-477
• Measuring the fluorescent quantum efficiency of indocynanine green encapsulated in nanocomposite particulates. Russin et al, 2010. Journal of Physics-Condensed Matter 22(33):334217
• Bioconjugation of Calcium Phosphosilicate Composite Nanoparticles for Selective Targeting of Human Breast and Pancreatic Cancers In Vivo. Barth et al, 2010. ACS Nano 4(3):1279-87
• Calcium Phosphate Nanocomposite Particles: A Safer and More Effective Alternative to Conventional Chemotherapy? Altinoglu et al, 2009. Future Oncology 5(3):279-281
• Photophysics of Cy3-encapsulated Calcium Phosphate Nanoparticles. Muddana et al, 2009. Nano Letters 9(4):1559-1566
• Shedding Light on tumors Using Nanoparticles. Rao. 2008. ACS Nano. 2:1984-1986
• Near-Infrared Nanoparticles Shine a Bright Light on Cancer. National Cancer Institute’s Alliance for Nanotechnology in Cancer -October 2008 Nanotech News
• Composite Nanoparticles Take Aim at Cancer. Gil et al, 2008. ACS Nano. 2(11):2200-2205
• Near-Infrared Emitting Fluorophore-Doped Calcium Phosphate Nanoparticles for In Vivo Imaging of Human Breast Cancer. Altinoglu et al, 2008. ACS Nano. 2(10):2075-2084
• Calcium Phosphate Nanocomposite Particles for In Vitro Imaging and Encapsulated Chemotherapeutic Drug Delivery to Cancer Cells. Kester et al, 2008. Nano Letters 8(12):4116-4121
• Encapsulation of Organic Molecules in Calcium Phosphate Nanocomposite Particles for Intracellular Imaging and Drug Delivery. Morgan et al, 2008. Nano Letters 8(12):4108-4115

Peer-reviewed publications surrounding Ceramide NanoLiposome Technology

• Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer. Yiang et al, 2011. 12(7)
• Ceramide-Based Therapeutics for the Treatment of Cancer. Barth et al, 2011. Cancer Biol Ther. 12(5)
• Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma. Tagaram et al, 2011. Gut 60(5):695-701
• Targeting of surviving by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia. Liu et al, 2011. Blood 116(20):4192-4201
• Metabolism of short-chain ceramide by human cancer cells – implications for therapeutic approaches. Chapman et al, 2010. Biochem Pharmacol 80(3):308-15
• Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development. Tran et al, 2008. Clin Cancer Res 14(11):3571-81
• Rapid distribution of liposomal short-chain ceramide in vitro and in vivo. Zolnik et al, 2008. Drug Metab Dispos 36(8):1709-15
• Ceramide recruits and activates protein kinase C zeta within structured membrane microdomains. Fox et al, 2007. J Biol Chem 282(17):12450-7
• The clinical potential of sphingolipid-based therapeutics. Fox et al, 2006. Cell Mol Life Sci 63(9):1017-23
• Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma. Stover et al, 2005. Clin Cancer Res 11(9):3465-74
• Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells. Stover et al, 2003. J Pharmacol Exp Ther 307(2):468-75
• Sphingolipids as therapeutics. Kester et al, 2003. Pharmacol Res 47(5):365-71
• Ceramide-induced inhibition of Akt is mediated through protein kinase C zeta: implications for growth arrest. Bourbon et al, 2002. J Biol Chem 277(5):3286-92
• Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions. Bourbon et al, 2001. Am J Physiol Cell Physiol 280(6):C1403-11
• Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. Bourbon et al, 2000. J Biol Chem 275(45):35617-23
• Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades. Coroneos et al, 1996. Biochem J 316 (pt1):13-17